About Us
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We are interested in the unique cell biology of early embryo development. We study how the zygotic genome awakens and the assembly of membraneless organelles. We are also interested in how cells regulate their dimensions. Our interdisciplinary team leverages tools and models from cell biology, chemistry, synthetic biology and developmental
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Genome activation at single cell level in space and time in blastula embryo
Synthetic cell-like compartments undergoing cell cycle
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Research INTERESTS
MEMBRANELESS
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We study how proteins self-organize into subcompartments inside the cell and engineer these organelles to control cell signaling and information processing
We are interested in mechanisms regulating the onset of genome activation in blastula stage embryos, as part of the maternal-zygotic transition. We investigate how embryos make decisions in early development. Additionally we are studying how collections of cells self-organize and pattern the cleavage stage embryo.
We study how cell and organelle size are regulated and how loss of scaling relationships contribute to disease We build synthetic cells and organelles as biomimetic systems and for delivery |